Dissertation Title:  “The role of T-cells in opioid analgesia”

Currently a Senior Scientist, Dept. of Neuroscience, University of Washington, St. Louis (srosen625@gmail.com)

  • Sorge, R.E., Martin, L.J., Isbester, K.A., Sotocinal, S.G., Rosen, S., Tuttle, A.H., Wieskopf, J.S., Acland, E.L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J.C.S., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A.P., Quinn, T., Frasnelli, J., Svensson, C.I., Sternberg, W.F., and Mogil, J.S. Olfactory exposure to males, including human males, stresses rodents. Nat. Meth., 11:629-632, 2014
  • Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat. Neurosci., 18:1081-1083, 2015
  • Rosen, S., Ham, B., and Mogil, J.S. Sex differences in neuroimmunity and pain. J. Neurosci. Res., 95:500-508, 2017
  • Rosen, S.F., Ham, B., Drouin, S., Boachie, N., Chabot-Dore, A.-J., Austin, J.-S., Diatchenko, L., and Mogil, J.S. T cell mediation of pregnancy analgesia affecting chronic pain in mice. J. Neurosci., 37:9819-9827, 2017
  • Rosen, S.F., Ham, B., Haichin, M., Walters, I., Tohyama, S., Sotocinal, S.G., and Mogil, J.S. Increased pain sensitivity and decreased opioid analgesia in T cell-deficient mice and implications for sex differences. Pain, 160:358-366, 2019
  • Zhang, H., Lecker, I., Collymore, C., Dokova, A., Pham, M.C., Rosen, S.F., Crawhall-Duk, H., Zain, M., Valencia, M., Filippini, H.F., Li, J., D’Souza, A.J., Cho, C., Michailidis, V., Whissell, P.D., Patel, I., Steenland, H.W., Lee, W.-J.V., Moayedi, M., Sterley, T.-L., Bains, J.S., Stratton, J.A., Matyas, J.R., Biernaskie, J., Dubins, D., Vukobradovic, I., Bezginov, A., Flenniken, A.M., Martin, L.J., Mogil, J.S., and Bonin, R.P. Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Pain, 162:1416-1425, 2021
  • Rosen, S.F., Lima, L.V., Chen, C., Nejade, R., Zhao, M., Nemoto, W., Toprak, E., Skvortsova, A., Tansley, S.N., Zumbusch, A., Sotocinal, S.G., Pittman, C., and Mogil, J.S. Olfactory exposure to late pregnant and lactating mice causes stress-induced analgesia in male mice. Sci. Adv., 8:eabi9366, 2022
  • Fan, C.Y., McAllister, B.B., Stokes-Heck, S., Harding, E.K., Pereira de Vasconcelos, A., Mah, L.K., Lima, L.V., van den Hoogen, N.J., Rosen, S.F., Ham, B., Zhang, Z., Burkhard, R., Geuking, M.B., Mahoney, D.J., Zamponi, G.W., Mogil, J.S., Ousman, S.S., and Trang, T. Divergent sex-specific pannexin-1 mechanisms in microglia and T-cells underlie neuropathic pain. Neuron, 113:896-911, 2025