The following is a list, in reverse chronological order, of primary research articles published by Dr. Mogil and colleagues:

 

Clarivate Highly Cited Paper (top 1% of field for its age): ♥

Clarivate Web of Science citations to date: ♦20+, ♦♦50+, ♦♦♦100+, ♦♦♦♦ 200+, ♦♦♦♦♦500+

Altmetric score: ⊕20+, ⊕⊕50+, ⊕⊕⊕100+, ⊕⊕⊕⊕200+, ⊕⊕⊕⊕⊕500+

 

  • McEachern, E.L.F., Zilic, M., Sotocinal, S.G., Ghasemlou,N., and Mogil, J.S. The timing of the mouse hind paw incision does not influence postsurgical pain. Neurobiology of Pain, 16:100161, 2024.   (DOI: 10.1016/j.ynpai.2024.100161)
  • Parisien, M., van Reij, R.R.I, Khoury, S., Koseli, E., Karaky, M., Silva, J.R. Taheri, G., van den Hoogen, N.J., Peng, G., Allegri, M., De Gregori, M., Chelly, J.E., Rakel, B.A., Aasvang, E.K., Kehlet, H., Buhre, W.F.F.A., Bryant, C.D., Damaj, M.I., King, I.L., Ghasemlou, N., Mogil, J.S., Joosten, E.A.J., and Diatchenko, L. Genome-wide association study identifies a protective role of B cells against chronic post-surgical pain. Br. J. Anaesthes., 133:360-370, 2024.   (DOI: 10.1016/j.bja.2024.04.053)
  • McCoy, E.S., Park, S.K., Patel, R.P., Ryan, D.F., Mullen, Z.J., Nesbitt, J.J., Lopez, J.E., Taylor-Blake, B., Vanden, K.A., Krantz, J.L., Hu, W., Garris, R.I., Snyder, M.G., Lima, L.V., Sotocinal, S.G., Austin, J.-S., Kashlan, A.D., Shah, S., Trocinski, A.K., Pudipeddi, S.S., Major, R.M., Bazick, H.O., Klein, M.R., Mogil, J.S., Wu, G., and Zylka, M.J. Development of PainFace software to simplify, standardize, and scale-up mouse grimace analysis. Pain, 165:1793-1805, 2024. (DOI: 10.1097/j.pain.000000000003187)
  • Zumbusch, A.S., McEachern, E.L.F., Morgan, O.B., Nickner, E., and Mogil, J.S. Normative preclinical algesiometry data on the von Frey and radiant heat paw-withdrawal tests: an analysis of data from more than 8,000 mice over 20 years. Journal of Pain, 25:104468, 2024. (DOI: 10.1016/j.pain.2024.01.333)
  • Nemoto, W., Kozak, D., Sotocinal, S.G., Tansley, S., Bannister, K., and Mogil, J.S. Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice. Pain, 164:1096-1105, 2023. (DOI: 10.1097/j.pain.00000000002806)
  • ⊕Millecamps, M., Sotocinal, S.G., Austin, J.-S., Stone, L.S., and Mogil, J.S. Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice. Pain, 164:577‑586, 2023. (DOI: 10.1097/j.pain.0000000000002742)
  • Roque, P.S., Perez, C.T., Hooshmandi, M., Wong, C., Eslamizade, M.J., Heshmati, S., Brown, N., Sharma, V., Lister, K.C., Goyon, V.M., Neagu-Lund, L., Shen, C., Daccache, N., Sato, H., Sato, T., Mogil, J.S., Nader, K., Gkogkas, C.G., Iordanova, M.D., Prager‑Khoutorsky, M., McBride, H.M., Lacaille, J.-C., Wykes, L., Schricker, T., and Khoutorsky, A. Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits. Journal of Clinical Investigation, 133:e159344, 2023. (DOI: 10.1172/JCI159344)
  • Wong, C., Barkai, O., Wang, F., Perez, C.T., Lev, S., Cai, W., Tansley, S., Yousefpour, N., Hooshmandi, M., Lister, K.C., Latif, M., Cuello, A.C., Prager-Khoutorsky, M., Mogil, J.S., Seguela, P., De Koninck, Y., Ribeiro-da-Silva, A., Binshtok, A.M., and Khoutorsky, A. mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation. Journal of Clinical Investigation, 132:e152635, 2022. (DOI: 10.1172/JCI152635)
  • ♦♦⊕⊕⊕Tansley, S., Gu, N., Guzman, A.U., Cai, W., Wong, C., Lister, K., Munoz-Pino, E., Yousefpour, N., Roome, R.B., Heal, J., Wu, N., Castonguay, A., Lean, G., Muir, E.M., Kania, A., Prager-Khoutorsky, M., Zhang, J., Gkogkas, C.G., Fawcett, J.W., Diatchenko, L., Ribeiro-da-Silva, A., De Koninck, Y., Mogil, J.S.*, and Khoutorsky, A.* Microglia-mediated degradation of perineuronal nets promotes pain. Science, 377:80-86, 2022. (*co-corresponding authors) (DOI: 10.1126/science.abl6773)
  • ⊕⊕⊕⊕⊕Rosen, S.F., Lima, L.V., Chen, C., Nejade, R., Zhao, M., Nemoto, W., Toprak, E., Skvortsova, A., Tansley, S.N., Zumbusch, A., Sotocinal, S.G., Pittman, C., and Mogil, J.S. Olfactory exposure to late pregnant and lactating mice causes stress-induced analgseia in male mice. Science Advances, 8:eabi9366, 2022. (DOI: 10.1126/sciadv.abi9366)
  • ♦♦♦⊕⊕⊕⊕⊕Parisien, M., Lima, L.V., Dagostino, C., El-Hachem, N., Drury, G.L., Grant, A.V., Huising, J., Verma, V., Meloto, C.B., Silva, J.R., Dutra, G.G.S., Markova, T., Dang, H., Tessier, P.A., Slade, G.D., Nackley, A.G., Ghasemlou, N., Mogil, J.S.*, Allegri, M.*, and Diatchenko, L.* Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Science Translational Medicine, 14:eabj9954, 2022. (*co-corresponding authors) (DOI: 10.1126/scitranslmed.abj9954)
  • ⊕Muralidharan, A., Sotocinal, S.G., Yousefpour, N., Akkurt, N., Lima, L.V., Tansley, S., Parisien, M., Wang, C., Austin, J.-S., Ham, B., Dutra, G.M.G.S., Rousseau, P., Maldonado-Bouchard, S., Clark, T., Rosen, S.F., Majeed, M.R., Silva, O., Nejade, R., Li, X., Donayre Pimentel, S., Nielsen, C.S., Neely, G.G., Autexier, C., Diatchenko, L., Ribeiro-da-Silva, A., and Mogil, J.S. Long-term male-specific chronic pain via telomere- and p53-mediated spinal cord cellular senescence. Journal of Clinical Investigation, 132:e151817, 2022.  (DOI: 10.1172/JCI151817)
  • ⊕Trask, S., Mogil, J.S., Helmstetter, F.J., Stucky, S.L., and Sadler, K.E. Contextual control of conditioned pain tolerance and endogenous analgesic systems. eLife, 11:e75283, 2022. (DOI: 10.7554/eLife.75283)
  • ♦♦⊕⊕Tansley, S., Uttam, S., Guzman, A.U., Yaqubi, M., Pacis, A., Parisien, M., Deamond, H., Wong, C., Rabau, O., Brown, N., Haglund, L., Ouellet, J., Santaguida, C., Ribeiro-da-Silva, A., Tahmasebi, S., Prager-Khoutorksy, M., Ragoussis, J., Zhang, J., Salter, M.W., Diatchenko, L., Healy, L.M.*, Mogil, J.S.*, and Khoutorsky, A.* Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain. Nature Communications, 13:843, 2022. (*co-corresponding authors) (DOI: 10.1038/s41467-022-28473-8)
  • ♦Khoury, S., Parisien, M., Thompson, S.J., Vachon-Presseau, E., Roy, M., Martinsen, A.E., Winsvold, B.S., HUNT All-In Pain, Mundal, I.P., Zwart, J.-A., Kania, A., Mogil, J.S., and Diatchenko, L. Genome-wide analysis identifies a distinct pathophysiology for chronic overlapping pain conditions via impaired axogenesis in the brain. Brain, 145:1111-1123, 2022. (DOI:  10.1093/brain/awab359)

  • Muralidharan, A., Samoshkin, A., Convertino, M., Piltonen, M.H., Gris, P., Wang, J., Jiang, C., Klares III, R., Linton, A., Ji, R.-R., Maixner, W., Dokholyan, N.V., Mogil, J.S., and Diatchenko, L. Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane mu-opioid receptor isoforms. British Journal of Pharmacology., 178:2709-2726, 2021. (DOI:  10.1111/bph.15463)

  • Meloto, C.B., Ingelmo, P., Perez, E.V., Pitt, R., Cardenas, V.H.G., Mohamed, N., Sotocinal, S.G., Bourassa, V., Lima, L.V., Ribeiro-da-Silva, A., Mogil, J.S., and Diatchenko, L. Mast cell stabilizer ketotifen fumarate reverses inflammatory but not neuropathic-induced mechanical pain in mice. Pain Reports, 6:e902, 2021. (DOI: 10.1097/PR9.0000000000000902)

  • ⊕Zhang, H., Lecker, I., Collymore, C., Dokova, A., Pham, M.C., Rosen, S.F., Crawhall-Duk, H., Zain, M., Valencia, M., Filippini, H.F., Li, J., D’Souza, A.J., Cho, C., Michailidis, V., Whissell, P.D., Patel, I., Steenland, H.W., Lee, W.-J.V., Moayedi, M., Sterley, T.-L., Bains, J.S., Stratton, J.A., Matyas, J.R., Biernaskie, J., Dubins, D., Vukobradovic, I., Bezginov, A., Flenniken, A.M., Martin, L.J., Mogil, J.S.*, and Bonin, R.P.* Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Pain, 162:1416-1425, 2021.   (*co-corresponding authors) (DOI: 10.1097/j.pain.0000000000002127)

  • ⊕Lister, K.C., Maldonado Bouchard, S., Markova, T., Aternali, A., Denecli, P., Donayre Pimentel, S., Majeed, M., Austin, J.-S., Williams, A.C.deC., and Mogil, J.S. Chronic pain produces hypervigilance to predator odor in mice. Current Biology, 30:R866-R867, 2020. (DOI: 10.1016/j.cub.2020.06.025) 
  • Muralidharan, A., Sotocinal, S.G., Austin, J.-S., and Mogil, J.S. The influence of aging and duration of injury on the anti-allodynic efficacy of analgesics in laboratory mice. Pain Reports, 5:e824, 2020. (DOI: 10.1097/PR9.0000000000000824)
  • ♦Linnstaedt, S.D., Rueckeis, C.A., Riker, K.D., Pan, Y., Wu, A., Yu, S., Wanstrath, B., Gonzalez, M., Harmon, E., Green, P., Chen, C., King, T., Lewandowski, C., Hendry, P.L., Pearson, C., Kurz, M.C., Datner, E., Velilla, M.A., Domeier, R., Liberzon, I., Mogil, J.S., Levine, J., and McLean, S.A. microRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure. Pain, 161:47-60, 2020. (DOI: 10.1097/j.pain.0000000000001709)
  • ♦Petitjean, H., Bourojeni, F.B., Tsao, D., Davidova, A., Sotocinal, S.G., Mogil, J.S., Kania, A., and Sharif-Naeini, R.  Recruitment of spinoparabrachial neurons by dorsal horn calretinin neurons. Cell Reports, 28:1429-1438, 2019. (DOI: 10.1016/j.celrep.2019.07.048)
  • ♦Parisien, M., Samoshkin, A., Tansley, S.N., Piltonen, M.H., Martin, L.J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J.S., Khoutorsky, A., and Diatchenko, L.  Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. Pain, 160:932-944, 2019. (DOI: 10.1097/j.pain.0000000000001471)
  • Tansley, S.N., Macintyre, L.C., Diamond, L., Sotocinal, S.G., George, N., Meluban, L., Austin, J.-S., Coderre, T.J., Martin, L.J., and Mogil, J.S. Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. Pain, 160:784-792, 2019. (DOI: 10.1097/j.pain.0000000000001454)
  • ♦Smith, S.B., Parisien, M., Bair, E., Belfer, I., Chabot-Dore, A.-J., Gris, P., Khoury, S. Tansley, S., Torosyan, Y., Zaykin, D.V., Bernhardt, O., de Oliveira Serrano, P., Gracely, R.H., Jain, D., Jarvelin, M.-R., Kaste, L.M., Kerr, K.F., Kocher, T., Lahdesmaki, R., Laniado, N., Laurie, C.C., Laurie, C.A., Mannikko, M., Meloto, C.B., Nackley, A.G., Nelson, S.C., Pesonen, P., Ribeiro-Dasilva, M.C., Rizzatti-Barbosa, C.M., Sanders, A.E., Schwahn, C., Sipila, K., Sofer, T., Teumer, A., Mogil, J.S., Fillingim, R.B., Greenspan, J.D., Ohrbach, R., Slade, G.D., Maixner, W., and Diatchenko, L. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain, 160:579-591, 2019. (DOI: 10.1097/j.pain.0000000000001438)
  • ♦⊕⊕⊕⊕Martin, L.J., Acland, E.L., Cho, C., Gandhi, W., Chen, D., Corley, E., Kadoura, B., Levy, T., Mirali, S., Tohyama, S., Khan, S., MacIntyre, L.C., Carlson, E.N., Schweinhardt, P., and Mogil, J.S. Male-specific conditioned pain hypersensitivity in mice and humans.  Current Biology, 29:192-201.e4, 2019. (DOI: 10.1016/j.cub.2018.11.030)
  • ♦♦Rosen, S., Ham, B., Haichin, M., Walters, I., Tohyama, S., Sotocinal, S.G., and Mogil, J.S. Increased pain sensitivity and decreased opioid analgesia in T cell-deficient mice and implications for sex differences. Pain, 160:358-366, 2019. (DOI: 10.1097/j.pain.0000000000001420) 
  • ♦Baskozos, G., Dawes, J.M., Austin, J.S., Antunes-Martins, A., McDermott, L., Clark, A.J., McMahon, S.B., Mogil, J.S., Orengo, C., and Bennett, D.L. Comprehensive analysis of long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury. Pain, 160:463-485, 2019. (DOI: 10.1097/j.pain.0000000000001416)
  • Tansley, S.N., Tuttle, A.H., Wu, N., Tohyama, S., Dossett, K., Gerstein, L., Ham, B., Austin, J.-S., Sotocinal, S.G., and Mogil, J.S. Modulation of social behavior and dominance status by chronic pain in mice.  Genes Brain and Behavior, 18:e12514, 2019. (DOI: 10.1111/gbb.12514)
  • ♦♦♦Mapplebeck, J.C.S., Dalgarno, R., Tu, Y.S., Moriarty, O., Beggs, S., Kwok, C.H.T., Halievski, K., Assi, S., Mogil, J.S., Trang, T., and Salter, M.W. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain, 159:1752-1763, 2018. (DOI: 10.1097/j.pain.0000000000001265) 
  • ♦Uttam, S., Wong, C., Amorim, I.S., Jafarnejad, S.M., Tansley, S.N., Yang, J., Prager-Khoutorsky, M., Mogil, J.S., Gkogkas, C.G., and Khoutorsky, A. Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain. Neurobiology of Pain, 4:35-44, 2018. (DOI: 10.1016/j.ynpai.2018.04.001) 
  • ♦♦⊕⊕⊕Tuttle, A.H., Molinaro, M.J., Jethwa, J.F., Sotocinal, S.G., Prieto, J.C., Styner, M.A., Mogil, J.S., and Zylka, M.J. A deep neural network to assess spontaneous pain from mouse facial expressions. Molecular Pain, 14:1-29, 2018. (DOI: 10.1177/1744806918763658)
  • ♦Rosen, S.F., Ham, B., Drouin, S., Boachie, N., Chabot-Dore, A.-J., Austin, J.-S., Diatchenko, L., and Mogil, J.S. T cell mediation of pregnancy analgesia affecting chronic pain in mice. Journal of Neuroscience, 37:9819-9827, 2017. (DOI: 10.1523/JNEUROSCI.2053-17.2017)
  • ♦♦⊕⊕⊕⊕Martin, L.J., Smith, S.B., Khoutorsky, A., Magnussen, C.A., Samoshkin, A., Sorge, R.E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khong, T.M., Mir, E., Gibson, D.G., Wieskopf, J.S., Sotocinal, S.G., Austin, J.-S., Meloto, C.B., Gitt, J.H., Gkogkas, C., Sonenberg, N., Greenspan, J., Fillingim, R.B., Ohrbach, R., Slade, G.D., Knott, C., Dubner, R., Nackley, A.G., Ribeiro-da-Silva, A., Neely, G.G., Maixner, W., Zaykin, D.V., Mogil, J.S.*, and Diatchenko, L.*  Epiregulin and EGFR interactions are involved in pain processing.  Journal of Clinical Investigation, 127:3353-3363, 2017.   (*co-corresponding authors) (DOI: 10.1172/JCI87406)
  • ♦♦Moy, J.K., Khoutorsky, A., Asiedu, M.N., Black, B.J., Kuh, J.L., Barragan-Iglesias, P., Megat, S., Burton, M.D., Burgos-Vega, C.C., Melemedjian, O.K., Boitano, S., Vagner, J., Gkogkas, C.G., Pancrazio, J.J., Mogil, J.S., Dussor, G., Sonenberg, N., and Price, T.J. The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. Journal of Neuroscience, 37:7481-7499, 2017. (DOI: 10.1523/JNEUROSCI.0220-17.2017) 
  • Parisien, M., Khoury, S., Chabot-Dore, A.-J., Sotocinal, S.G., Slade, G.D., Smith, S.B., Fillingim, R.B., Ohrbach, R., Greenspan, J.D., Maixner, W., Mogil, J.S., Belfer, I., and Diatchenko, L. Effect of human genetic variability on gene transcription in dorsal root ganglia and association with pain phenotypes. Cell Reports, 19:1940-1952, 2017. (DOI: 10.1016/j.celrep.2017.05.018)
  • Tuttle, A.H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O., Yachnin, D., Austin, J.-S., Chan, C.M., Groves, I., Pooters, T., Martin, L.J., Sonenberg, N., Gkogkas, C.G., and Mogil, J.S. Social propinquity in rodents as measured by tube co-occupancy differs between inbred and outbred genotypes.  Proceedings of the National Academy of Sciences, USA, 114:5515-5520, 2017. (DOI: 10.1073/pnas.1703477114)
  • ♦Khoutorsky, A., Sorge, R.E., Prager-Khoutorsky, M., Pawlowski, S.A., Longo, G., Jafarnejad, S.M., Tahmasebi, S., Martin, L.J., Pitcher, M.H., Gkogkas, C.G., Sharif-Naeini, R., Ribeiro-da-Silva, A., Bourque, C.W., Cervero, F., Mogil, J.S.*, and Sonenberg, N.* eIF2a phosphorylation controls thermal nociception. Proceedings of the National Academy of Sciences, USA, 113:11949-11954, 2016.  (*co-corresponding authors) (DOI: 10.1073/pnas1614047113)
  • ♦Ultsch, A., Kringel, D., Kalso, E., Mogil, J.S., and Lotsch, J. A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity. Pain, 157:2747-2757, 2016. (DOI: 10.1097/j.pain.0000000000000694)
  • Kikusui, T., Ishio, Y., Nagasawa, M., Mogil, J.S., and Mogi, K. Early weaning impairs a social contagion of pain-related stretching behavior in mice. Developmental Psychobiology, 58:1101-1107, 2016. (DOI: 10.1002/dev.21443)
  • ⊕⊕⊕Young, E., Bryant, C., Lee, S., Nair, H., Dreher, K., Zhang, X., Palmer, A., Chung, J.M., Mogil, J.S., Chesler, E., and Lariviere, W. Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes Brain and Behavior, 15:604-615, 2016. (DOI: 10.1111/gbb.12302)
  • ♦Kahle, K.T., Schmouth, J.F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganiere, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J.C., Sotocinal, S.G., Duan, J., Ward, C., Khanna, A.R., Mogil, J.S., Dion, P.A., Woolf, C.J., Inquimbert, P., and Rouleau, G.A. Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.  Science Signaling. 9:ra32, 2016. (DOI: 10.1126/scisignal.aad0163)
  • ♦♦⊕⊕⊕Daou, I., Beaudry, H., Ase, A.R., Wieskopf, J.S., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P. Optogenetic silencing of Nav1.8-positive afferents alleviates inflammatory and neuropathic pain. eNeuro, 3: e0140-15.2016, 2016. (DOI: 10.1523/ENEURO.0140-15.2016) 
  • Samoshkin, A., Convertino, M., Viet, C.T., Wieskopf, J.S., Marcovitz, J., Patel, P., Stone, L., Maixner, W., Mogil, J.S., Schmidt, B.L., Dokholyan, N.V., and Diatchenko, L.  Structural and functional interaction between six transmembrane μ-opioid receptor isoform and β2-adrenoceptors.  Science Reports, 5:18198, 2015. (DOI: 10.1038/srep18198)
  • ♦Khoutorsky, A., Bonin, R.P., Sorge, R.E., Gkogkas, C., Pawlowski, S.A., Jafarnejad, S.M., Pitcher, M.H., Alain, T., Perez-Sanchez, J. Salter, E.W., Martin, L.J., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J.S.* and Sonenberg, N.* Translational control of nociception via 4E-binding protein 1. eLife, 4:e12002, 2015.   (*co-corresponding authors) (DOI: 10.7554/eLife.12002)      
  • ♦Martin, L.J., Piltonen, M.H., Gauthier, J., Convertino, M., Acland, E.L., Dokholyan, N.V., Mogil, J.S., Diatchenko, L., and Maixner, W.  Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers. Journal of Pain, 16:1321-1333, 2015. (DOI: 10.1016/j.jpain.2015.09.004)
  • ♥♦♦♦♦⊕⊕⊕⊕⊕Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nature Neuroscience, 18:1081-1083, 2015. (DOI: 10.1038/nn.4053) 
  • Segall, S.K., Shabalina, S.A., Meloto, C.B., Wen, X., Gauthier, J., Wiltshire, T., Cunningham, D., Tarantino, L., Tohyama, S., Martin, L.J., Mogil, J.S., and Diatchenko, L. Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. Pain, 156:1965-1977, 2015. (DOI: 10.1097/j.pain.0000000000000258)
  • Wieskopf, J.S., Mathur, J. Limapichat, W., Post, M.R., Al-Qazzaz, M., Sorge, R.E., Martin, L.J., Zaykin, D.V., Smith, S.B., Freitas, K., Austin, J.-S., Dai, F., Zhang, J., Marcovitz, J., Tuttle, A.H., Slepian, P.M., Clarke, S., Drenan, R.M., Janes, J., Al Sharari, S., Segall, S.K., Aasvang, E.K., Lai, W., Bittner, R., Richards, C.I., Slade, G.D., Kehlet, H., Walker, J., Maskos, U., Changeux, J.-P., Devor, M., Maixner, W., Diatchenko, L., Belfer, I., Dougherty, D.A., Su, A.I., Lummis, S.C.R., Damaj, M.I., Lester, H.A., Patapoutian, A., and Mogil, J.S. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine, 7:287ra72, 2015. (DOI: 10.1126/scitranslmed.3009986)
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  • ♦Sternberg, W.F., Ritchie, J., and Mogil, J.S. Qualitative sex differences in kappa-opioid analgesia in mice are dependent on age. Neuroscience Letters, 363:178-181, 2004. (DOI: 10.1016/j.neulet.2004.04.004)
  • ♦♦Nemmani, K.V.S., Grisel, J.E., Stowe, J.R., Smith-Carliss, R., and Mogil, J.S. Modulation of morphine analgesia by site-specific N-methyl-D-aspartate receptor antagonists: dependence on sex, site of antagonism, morphine dose, and time. Pain, 109:274-283, 2004. (DOI: 10.1016/j.pain.2004.01.035)
  • ♦♦♦Smith, S.B., Crager, S.E., and Mogil, J.S. Paclitaxel-induced neuropathic hypersensitivity in mice: responses in 10 inbred mouse strains. Life Sciences, 74:2593-2604, 2004. (DOI: 10.1016/j.lfs.2004.01.002)
  • ♦♦Chesler, E.J., Ritchie, J., Kokayeff, A., Lariviere, W.R., Wilson, S.G., and Mogil, J.S. Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited. Pain, 106:325-335, 2003. (DOI: 10.1016/S0304-3959(03)00330-0)
  • ♦♦Bon, K., Lichtensteiger, C.A., Wilson, S.G., and Mogil, J.S. Characterization of cyclophosphamide cystitis, a model of visceral and referred pain, in the mouse: species and strain differences. Journal of Urology, 170:1008-1012, 2003. (DOI: 10.1097/01.ju.0000079766.49550.94)
  • ♦Wilson, S.G., Bryant, C.D., Lariviere, W.R., Olsen, M.S., Giles, B.E., Chesler, E.J., and Mogil, J.S. The heritability of antinociception II:  pharmacogenetic mediation of three over-the-counter analgesics in mice. Journal of Pharmacology and Experimental Therapeutics, 305:755-764, 2003. (DOI: 10.1124/jpet.102.047902)
  • ♦♦♦♦Mogil, J.S., Wilson, S.G., Chesler, E.J., Rankin, A.J., Nemmani, K.V.S., Lariviere, W.R., Groce, M.K., Wallace, M.R., Kaplan, L., Staud, R., Ness, T.J., Glover, T.L., Stankova, M., Mayorov, A., Hruby, V.J., Grisel, J.E., and Fillingim, R.B. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.  Proceedings of the National Academy of Sciences, USA, 100:4867-4872, 2003. (DOI: 10.1073/pnas.0730053100)
  • ♦Nemmani, K.V.S. and Mogil, J.S. Serotonin-GABA interactions in the modulation of mu- and kappa-opioid analgesia. Neuropharmacology, 44:304-310, 2003. (DOI: 10.1016/S0028-3908(02)00374-X)
  • ♦♦Wilson, S.G., Smith, S.B., Chesler, E.J., Melton, K.A., Haas, J.J., Mitton, B., Strasburg, K., Hubert, L., Rodriguez-Zas, S.L., and Mogil, J.S. The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics. Journal of Pharmacology and Experimental Therapeutics, 304:547-559, 2003. (DOI: 10.1124/jpet.102.041889)
  • ♦♦♦♦Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S. Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neuroscience and Biobehavioral Reviews, 26:907-923, 2002. (DOI: 10.1016/S0149-7634(02)00103-3)
  • ♦♦Kest, B., Palmese, C.A., Hopkins, E., Adler, M., Juni, A., and Mogil, J.S. Naloxone-precipitated withdrawal jumping in 11 inbred mouse strains: evidence for common genetic mechanisms in acute and chronic morphine physical dependence. Neuroscience, 115:463-469, 2002. (DOI: 10.1016/S0306-4522(02)00458-X)
  • ♦♦♦♦Chesler, E.J., Wilson, S.G., Lariviere, W.R., Rodriguez-Zas, S.L., and Mogil, J.S. Influences of laboratory environment on behavior. Nature Neuroscience, 5:1101-1102, 2002. (DOI: 10.1038/nn1102-1101)
  • ♦♦Kest, B., Hopkins, E., Palmese, C.A., Adler, M., and Mogil, J.S.  Genetic variation in morphine analgesic tolerance: a survey of 11 inbred mouse strains. Pharmacology, Biochemistry and Behavior, 73:821-828, 2002. (DOI: 10.1016/S0091-3057(02)00908-5)
  • ♦Bon, K., Wilson, S.G., Mogil, J.S., and Roberts, W.J. Genetic evidence for the correlation of deep dorsal horn Fos protein immunoreactivity with tonic formalin pain behavior. Journal of Pain, 3:181-189, 2002. (DOI: 10.1054/jpai.2002.123710)
  • ♦♦♦Lariviere, W.R., Wilson, S.G., Laughlin, T.M., Kokayeff, A., West, E.E., Adhikari, S.M., Wan, Y., and Mogil, J.S. Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity. Pain, 97:75-86, 2002. (DOI: 10.1016/S0304-3959(01)00492-4)
  • ♦Wilson, S.G., Chesler, E.J., Hain, H., Rankin, A.J., Schwarz, J.Z., Call, S.B., Murray, M.R., West, E.E., Teuscher, C., Rodriguez-Zas, S., Belknap, J.K., and Mogil, J.S. Identification of quantitative trait loci for chemical/inflammatory nociception in mice. Pain, 96:385-391, 2002. (DOI: 10.1016/S0304-3959(01)00489-4)
  • ♦Rizzi, A., Marzola, G., Bigoni, R., Guerrini, R., Salvadori, S., Mogil, J.S., Regoli, D., and Calo’, G.  Endogenous nociceptin signaling and stress-induced analgesia. Neuroreport, 12:3009-3013, 2001. (DOI: 10.1097/00001756-200110080-00006)
  • ♦♦Bergeson, S.E., Helms, M.L., O’Toole, L.A., Jarvis, M.W., Hain, H.S., Mogil, J.S., and Belknap, J.K.  Quantitative trait loci influencing morphine antinociception in four mapping populations. Mammalian Genome, 12:546-553, 2001. (DOI: 10.1007/s003350020022)
  • ♦Kest, B., Hopkins, E., Palmese, C.A., Chen, Z.-P., Mogil, J.S., and Pintar, J.E. Morphine tolerance and dependence in nociceptin/orphanin FQ transgenic knock-out mice. Neuroscience, 104:217-222, 2001. (DOI: 10.1016/S0306-4522(01)00037-9)
  • ♦♦Wan, Y., Wilson, S.G., Han, J.S., and Mogil, J.S. The effect of genotype on sensitivity to electroacupuncture analgesia. Pain, 91:5-13, 2001. (DOI: 10.1016/S0304-3959(00)00416-4)
  • Mogil, J.S., Grisel, J.E., Bales, J.R., Hayward, M.D., Rubinstein, M., Belknap, J.K.,and Low, M. Disparate spinal and supraspinal opioid antinociceptive responses in β-endorphin-deficient mutant mice.  Neuroscience, 101:709-717, 2000. (DOI: 10.1016/S0306-4522(00)00422-X)
  • ♦♦♦♦Mogil, J.S., Chesler, E.J., Wilson, S.G., Juraska, J.M., and Sternberg, W.F.  Sex differences in thermal nociception and morphine antinociception in the rodent depend on genotype. Neuroscience and Biobehavioral Reviews, 24:375-389, 2000. (DOI: 10.1016/S0149-7634(00)00015-4)
  • ♦Hain, H., Belknap, J.K., and Mogil, J.S. Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity. Journal of Pharmacology and Experimental Therapeutics, 291:444-449, 1999. (PMID: 10525057)
  • ♦Flores, C.M, Wilson, S.G., and Mogil, J.S. Pharmacogenetic variability in neuronalnicotinic receptor-mediated antinociception. Pharmacogenetics, 9:619-625, 1999. (DOI: 10.1097/00008571-199910000-00008)
  • ♦♦Grisel, J.E., Mogil, J.S., Grahame, N.J., Rubinstein, M., Belknap, J.K., Crabbe, J.C., and Low, M.  Ethanol oral self-administration is increased in mutant mice with decreased β-endorphin expression. Brain Research, 835:62-67, 1999. (DOI: 10.1016/S0006-8993(99)01384-0)
  • ♦♦♦Kest, B., Wilson, S.G., and Mogil, J.S. Sex differences in supraspinal morphine analgesia are dependent on genotype.  Journal of Pharmacology and Experimental Therapeutics, 289:1370-1375, 1999. (PMID: 10336528)
  • ♦♦Martìnez, V., Thakur, S., Mogil, J.S., Tachë, Y., and Mayer, E.A. Differential effects of chemical and mechanical colonic irritation on behavioral pain response to intraperitoneal acetic acid in mice. Pain, 81:179-186, 1999. (DOI: 10.1016/S0304-3959(99)00008-1)
  • ♦♦♦♦Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M. Heritability of nociception. II. ‘Types’ of nociception revealed by genetic correlation analysis. Pain, 80:83-93, 1999. (DOI: 10.1016/S0304-3959(98)00196-1)
  • ♦♦♦♦♦Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M. Heritability of nociception. I. Responses of eleven inbred mouse strains on twelve measures of nociception. Pain, 80:67-82, 1999. (DOI: 10.1016/S0304-3959(98)00197-3)
  • ♦Mogil, J.S., Nessim, L.A., and Wilson, S.G. Strain-dependent effects of supraspinal orphanin FQ/nociceptin on thermal nociceptive sensitivity in mice. Neuroscience Letters, 261:147-150, 1999. (DOI: 10.1016/S0304-3940(99)00012-9)
  • ♦Kest, B., Jenab, S., Brodsky, M., Sadowski, B., Belknap, J.K., Mogil, J.S., and Inturrisi, C.E. Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia. Brain Research, 816:381-389, 1999. (DOI: 10.1016/S0006-8993(98)01141-X)
  • Kest, B., McLemore, G.L., Sadowski, B., Mogil, J.S., Belknap, J.K., and Inturrisi, C.E. Acute morphine dependence in mice selectively-bred for high and low analgesia. Neuroscience Letters, 256:120-122, 1998. (DOI: 10.1016/S0304-3940(98)00772-1)
  • Kest, B., Beckzowska, I., Franklin, S.O., Lee, C.E., Mogil, J.S., and Inturrisi, C.E. Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice. Brain Research, 805:131-137, 1998. (DOI: 10.1016/S0006-8993(98)00696-9)
  • ♦Grisel, J.E., Farrier, D.E., Wilson, S.G., and Mogil, J.S. [Phe1Y(CH2-NH)Gly2] nociception-(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivo. European Journal of Pharmacology, 357:R1-R3, 1998. (DOI: 10.1016/S0014-2999(98)00567-6)
  • ♦Mogil, J.S., Lichtensteiger, C.A., and Wilson, S.G. The effect of genotype on sensitivity to inflammatory nociception: characterization of resistant (A/J) and sensitive (C57BL/6J) inbred mouse strains. Pain, 76:115-125, 1998. (DOI: 10.1016/S0304-3959(98)00032-3)
  • ♦♦Mogil, J.S., Shin, Y.-H., McCleskey, E.W., Kim, S.-C., and Nah, S.-Y. Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. Brain Research, 792:218-228, 1998. (DOI: 10.1016/S0006-8993(98)00133-4)
  • ♦♦Sufka, K.J., Watson, G.S., Nothdurft, R.E., and Mogil, J.S. Scoring the mouse formalin test: validation study. European Journal of Pain, 2:351-358, 1998. (DOI: 10.1016/S1090-3801(98)90033-7)
  • ♦♦Mogil, J.S. and Wilson, S.G. Nociceptive and morphine antinociceptive sensitivity of 129 and C57BL/6 inbred mouse strains: implications for transgenic knock-out studies. European Journal of Pain, 1:293-297, 1997. (DOI: 10.1016/S1090-3801(97)90038-0)
  • ♦♦Mogil, J.S., Richards, S.P., O’Toole, L.A., Mitchell, S.R., Helms, M.L., Kest, B., and Belknap, J.K. Identification of sex-specific quantitative trait loci mediating non-opioid swim stress-induced analgesia in female mice.  Journal of Neuroscience, 17:7995-8002, 1997. (DOI: 10.1523/JNEUROSCI.17-20-07995.1997)
  • ♦♦♦Mogil, J.S., Richards, S.P., O’Toole, L.A., Helms, M.L., Mitchell, S.R., and Belknap, J.K. Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by δ2-opioid receptors. Pain, 70:267-277, 1997. (DOI: 10.1016/S0304-3959(97)03333-2)
  • ♦♦♦♦Tian, J.-H., Xu, W., Fang, Y., Mogil, J.S., Grisel, J.E., Grandy, D.K., and Han, J.-S. Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat. British Journal of Pharmacology, 120:676-680, 1997. (DOI: 10.1038/sj.bjp.0700942)
  • Kest, B., Lee, C.E., Mogil, J.S., and Inturrisi, C.E. Blockade of morphine supersensitivity by an antisense oligodeoxynucleotide targeting the delta opioid receptor (DOR-1). Life Sciences, 60:PL155-159, 1997. (DOI: 10.1016/S0024-3205(96)00704-7)
  • ♦♦Tian, J.-H., Xu, W., Fang, Y., Grisel, J.E., Mogil, J.S., Grandy, D.K., and Han, J.-S. Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia. Neuroreport, 8:497-500, 1997. (DOI: 10.1097/00001756-199701200-00024)
  • ♦♦Mogil, J.S. and Belknap, J.K. Sex and genotype determine the selective activation of neurochemically-distinct forms of swim stress-induced analgesia. Pharmacology, Biochemistry and Behavior, 56:61-66, 1997. (DOI: 10.1016/S0091-3057(96)00157-8)
  • ♦♦♦♦Mogil, J.S., Grisel, J.E., Reinscheid, R.K., Civelli, O., Belknap, J.K., and Grandy, D.K.  Orphanin FQ is a functional anti-opioid peptide. Neuroscience, 75:333-337, 1996. (DOI: 10.1097/00001756-199609020-00012)
  • ♦♦♦Grisel, J.E., Mogil, J.S., Belknap, J.K., and Grandy, D.K. Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide.  Neuroreport, 7:2125-2129, 1996. (DOI: 10.1097/00001756-199609020-00012)
  • ♦♦♦♦Mogil, J.S., Grisel, J.E., Zhang, G., Belknap, J.K., and Grandy, D.K.  Functional antagonism of μ-, δ- and κ-opioid antinociception by orphanin FQ. Neuroscience Letters, 214:131-134, 1996. (DOI: 10.1016/0304-3940(96)12917-7)
  • ♦♦♦♦Rubinstein, M.*, Mogil, J.S.*, Japón, M., Chan, E.C., Allen, R.G., and Low, M.J. Absence of opioid stress-induced analgesia in mice lacking β-endorphin by site-directed mutagenesis. Procedings of the National Academy of Sciences, USA, 93:3995-4000, 1996. (*co-first authors) (DOI: 10.1073/pnas.93.9.3995)
  • ♦♦♦Mogil, J.S., Kest, B., Sadowski, B., and Belknap, J.K. Differential genetic mediation of sensitivity to morphine in genetic models of opiate sensitivity: influence of nociceptive assay. Journal of Pharmacology and Experimental Therapeutics, 276: 532-544, 1996. (PMID: 8632319)
  • ♦♦♦Mogil, J.S., Sternberg, W.F., Balian, H., Liebeskind, J.C., and Sadowski, B. Opioid and non-opioid swim stress-induced analgesia: a parametric analysis in mice. Physiology and Behavior, 59: 123-132, 1996. (DOI: 10.1016/0031-9384(95)02073-X)
  • Kest, B., Brodsky, M., Sadowski, B., Mogil, J.S., and Inturrisi, C.E. Mu-opiate receptor (Mor-1) mRNA levels are altered in mice with differential analgesic sensitivity to the mu agonist, DAMGO. Analgesia, 1:498-501, 1995. (not MEDLINE indexed)
  • ♦♦Sternberg, W.F., Mogil, J.S., Kest, B., Page, G.G., Leong, Y., Yam, V., and Liebeskind, J.C. Neonatal testosterone exposure influences neurochemistry of swim stress-induced analgesia in adult mice. Pain, 63:321-326, 1995. (DOI: 10.1016/0304-3959(95)00059-3)
  • Mogil, J.S., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines. Behavior Genetics, 25:397-406, 1995. (DOI: 10.1007/BF02197290)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C. 1,3-Di-o-tolylguanidine (DTG) differentially affects acute and tonic formalin pain: antagonism by rimcazole. Pharmacology, Biochemistry and Behavior, 52:175-178, 1995. (DOI: 10.1016/0091-3057(95)00085-B)
  • Vaccarino, F.J., Mogil, J.S., and Stinus, L. Chronic dopamine antagonism facilitates opiate-induced feeding. Journal of Psychiatric Neuroscience, 20:210-214, 1995. (PMID: 7786882) 
  • ♦♦Belknap, J.K., Mogil, J.S., Helms, M.L., O’Toole, L.A., Richards, S.P., and Bergeson, S.E. Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 mouse strains.  Life Sciences, 57:PL117-124, 1995. (DOI: 10.1016/0024-3205(95)02040-P)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C. Antinociception following 1,3-di-o-tolylguanidine (DTG), a selective sigma receptor ligand. Pharmacology, Biochemistry and Behavior, 50:587-592, 1995. (DOI: 10.1016/0091-3057(94)00346-7)
  • ♦Mogil, J.S., Marek, P., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., and Liebeskind, J.C. One or two genetic loci mediate high opiate analgesia in selectively bred mice. Pain, 60:125-135, 1995. (DOI: 10.1016/0304-3959(94)00098-Y)
  • ♦♦Mogil, J.S., Marek, P., O’Toole, L.A., Helms, M.L., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia.  Brain Research, 653:16-22, 1994. (DOI: 10.1016/0006-8993(94)90366-2)
  • ♦♦♦♦Mogil, J.S., Sternberg, W.F., Kest, B., Marek, P., and Liebeskind, J.C. Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement. Pain, 253:17-25, 1993. (DOI: 10.1016/0304-3959(93)90050-Y)
  • ♦Marek, P., Mogil, J.S., Belknap, J.K., Sadowski, B., and Liebeskind, J.C.  Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalties. Brain Research, 608:353-357, 1993. (DOI: 10.1016/0006-8993(93)91479-C)
  • ♦Mogil, J.S., Marek, P., Yirmiya, R., Balian, H., Sadowski, B., Taylor, A.N., and Liebeskind, J.C. Antagonism of the non-opioid component of ethanol-induced analgesia by the NMDA receptor antagonist MK-801. Brain Research, 602:126-130, 1993. (DOI: 10.1016/0006-8993(93)90251-H)
  • ♦♦Marek, P., Mogil, J.S., Sternberg, W.F., Panocka, I., and Liebeskind, J.C. N-Methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 blocks non-opioid stress-induced analgesia. II. Studies using three different water temperature paradigms and selectively bred mice. Brain Research, 578:197-203, 1992. (DOI: 10.1016/0006-8993(92)90248-8)
  • ♦♦♦Ben-Eliyahu, S., Marek, P., Vaccarino, A.L., Mogil, J.S., Sternberg, W.F., and Liebeskind, J.C. The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat. Brain Research, 575:304-308, 1992. (DOI: 10.1016/0006-8993(92)90094-P)