The following is a list, in reverse chronological order, of primary research articles published by Dr. Mogil and colleagues:

 

Clarivate Highly Cited Paper (top 1% of field for its age):

Clarivate Web of Science citations to date: 20+, ♦♦50+, ♦♦♦100+, ♦♦♦♦ 200+, ♦♦♦♦♦500+

Altmetric score: 20+, ⊕⊕50+, ⊕⊕⊕100+, ⊕⊕⊕⊕200+, ⊕⊕⊕⊕⊕500+

 

 

  • ⊕⊕Tansley, S., Gu, N., Guzman, A.U., Cai, W., Wong, C., Lister, K., Munoz-Pino, E., Yousefpour, N., Roome, R.B., Heal, J., Wu, N., Castonguay, A., Lean, G., Muir, E.M., Kania, A., Prager-Khoutorsky, M., Zhang, J., Gkogkas, C.G., Fawcett, J.W., Diatchenko, L., Ribeiro-da-Silva, A., De Koninck, Y., Mogil, J.S.*, and Khoutorsky, A.* Microglia-mediated degradation of perineuronal nets promotes pain. Science, in press. (*co-corresponding authors) (DOI: 10.1126/science.abl6773)
  • ⊕⊕⊕Rosen, S.F., Lima, L.V., Chen, C., Nejade, R., Zhao, M., Nemoto, W., Toprak, E., Skvortsova, A., Tansley, S.N., Zumbusch, A., Sotocinal, S.G., Pittman, C., and Mogil, J.S. Olfactory exposure to late pregnant and lactating mice causes stress-induced analgseia in male mice. Science Advances, 8:eabi9366, 2022. (DOI: 10.1126/sciadv.abi9366)
  • Parisien, M., Lima, L.V., Dagostino, C., El-Hachem, N., Drury, G.L., Grant, A.V., Huising, J., Verma, V., Meloto, C.B., Silva, J.R., Dutra, G.G.S., Markova, T., Dang, H., Tessier, P.A., Slade, G.D., Nackley, A.G., Ghasemlou, N., Mogil, J.S.*, Allegri, M.*, and Diatchenko, L.* Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Science Translational Medicine, 14:eabj9954, 2022. (*co-corresponding authors) (DOI: 10.1126/scitranslmed.abj9954)
  • Muralidharan, A., Sotocinal, S.G., Yousefpour, N., Akkurt, N., Lima, L.V., Tansley, S., Parisien, M., Wang, C., Austin, J.-S., Ham, B., Dutra, G.M.G.S., Rousseau, P., Maldonado-Bouchard, S., Clark, T., Rosen, S.F., Majeed, M.R., Silva, O., Nejade, R., Li, X., Donayre Pimentel, S., Nielsen, C.S., Neely, G.G., Autexier, C., Diatchenko, L., Ribeiro-da-Silva, A., and Mogil, J.S. Long-term male-specific chronic pain via telomere- and p53-mediated spinal cord cellular senescence. Journal of Clinical Investigation, 132:e151817, 2022.  (DOI: 10.1172/JCI151817)
  • Trask, S., Mogil, J.S., Helmstetter, F.J., Stucky, S.L., and Sadler, K.E. Contextual control of conditioned pain tolerance and endogenous analgesic systems. eLife, 11:e75283, 2022. (DOI: 10.7554/eLife.75283)
  • ⊕⊕Tansley, S., Uttam, S., Guzman, A.U., Yaqubi, M., Pacis, A., Parisien, M., Deamond, H., Wong, C., Rabau, O., Brown, N., Haglund, L., Ouellet, J., Santaguida, C., Ribeiro-da-Silva, A., Tahmasebi, S., Prager-Khoutorksy, M., Ragoussis, J., Zhang, J., Salter, M.W., Diatchenko, L., Healy, L.M.*, Mogil, J.S.*, and Khoutorsky, A.* Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain. Nature Communications, 13:843, 2022. (*co-corresponding authors) (DOI: 10.1038/s41467-022-28473-8)
  • Khoury, S., Parisien, M., Thompson, S.J., Vachon-Presseau, E., Roy, M., Martinsen, A.E., Winsvold, B.S., HUNT All-In Pain, Mundal, I.P., Zwart, J.-A., Kania, A., Mogil, J.S., and Diatchenko, L. Genome-wide analysis identifies a distinct pathophysiology for chronic overlapping pain conditions via impaired axogenesis in the brain. Brain, 145:1111-1123, 2022. (DOI:  10.1093/brain/awab359)
  • Muralidharan, A., Samoshkin, A., Convertino, M., Piltonen, M.H., Gris, P., Wang, J., Jiang, C., Klares III, R., Linton, A., Ji, R.-R., Maixner, W., Dokholyan, N.V., Mogil, J.S., and Diatchenko, L. Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane mu-opioid receptor isoforms. British Journal of Pharmacology., 178:2709-2726, 2021. (DOI:  10.1111/bph.15463)

  • Meloto, C.B., Ingelmo, P., Perez, E.V., Pitt, R., Cardenas, V.H.G., Mohamed, N., Sotocinal, S.G., Bourassa, V., Lima, L.V., Ribeiro-da-Silva, A., Mogil, J.S., and Diatchenko, L. Mast cell stabilizer ketotifen fumarate reverses inflammatory but not neuropathic-induced mechanical pain in mice. Pain Reports, 6:e902, 2021. (DOI: 10.1097/PR9.0000000000000902)

  • Zhang, H., Lecker, I., Collymore, C., Dokova, A., Pham, M.C., Rosen, S.F., Crawhall-Duk, H., Zain, M., Valencia, M., Filippini, H.F., Li, J., D’Souza, A.J., Cho, C., Michailidis, V., Whissell, P.D., Patel, I., Steenland, H.W., Lee, W.-J.V., Moayedi, M., Sterley, T.-L., Bains, J.S., Stratton, J.A., Matyas, J.R., Biernaskie, J., Dubins, D., Vukobradovic, I., Bezginov, A., Flenniken, A.M., Martin, L.J., Mogil, J.S.*, and Bonin, R.P.* Cage-lid hanging behavior as a translationally relevant measure of pain in mice. Pain, 162:1416-1425, 2021.   (*co-corresponding authors) (DOI: 10.1097/j.pain.0000000000002127)

  • Lister, K.C., Maldonado Bouchard, S., Markova, T., Aternali, A., Denecli, P., Donayre Pimentel, S., Majeed, M., Austin, J.-S., Williams, A.C.deC., and Mogil, J.S. Chronic pain produces hypervigilance to predator odor in mice. Current Biology, 30:R866-R867, 2020. (DOI: 10.1016/j.cub.2020.06.025) 
  • Muralidharan, A., Sotocinal, S.G., Austin, J.-S., and Mogil, J.S. The influence of aging and duration of injury on the anti-allodynic efficacy of analgesics in laboratory mice. Pain Reports, 5:e824, 2020. (DOI: 10.1097/PR9.0000000000000824)
  • Linnstaedt, S.D., Rueckeis, C.A., Riker, K.D., Pan, Y., Wu, A., Yu, S., Wanstrath, B., Gonzalez, M., Harmon, E., Green, P., Chen, C., King, T., Lewandowski, C., Hendry, P.L., Pearson, C., Kurz, M.C., Datner, E., Velilla, M.A., Domeier, R., Liberzon, I., Mogil, J.S., Levine, J., and McLean, S.A. microRNA-19b predicts widespread pain and posttraumatic stress symptom risk in a sex-dependent manner following trauma exposure. Pain, 161:47-60, 2020. (DOI: 10.1097/j.pain.0000000000001709)
  • Petitjean, H., Bourojeni, F.B., Tsao, D., Davidova, A., Sotocinal, S.G., Mogil, J.S., Kania, A., and Sharif-Naeini, R.  Recruitment of spinoparabrachial neurons by dorsal horn calretinin neurons. Cell Reports, 28:1429-1438, 2019. (DOI: 10.1016/j.celrep.2019.07.048)
  • Parisien, M., Samoshkin, A., Tansley, S.N., Piltonen, M.H., Martin, L.J., El-Hachem, N., Dagostino, C., Allegri, M., Mogil, J.S., Khoutorsky, A., and Diatchenko, L.  Genetic pathway analysis reveals a major role for extracellular matrix organization in inflammatory and neuropathic pain. Pain, 160:932-944, 2019. (DOI: 10.1097/j.pain.0000000000001471)
  • Tansley, S.N., Macintyre, L.C., Diamond, L., Sotocinal, S.G., George, N., Meluban, L., Austin, J.-S., Coderre, T.J., Martin, L.J., and Mogil, J.S. Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. Pain, 160:784-792, 2019. (DOI: 10.1097/j.pain.0000000000001454)
  • Smith, S.B., Parisien, M., Bair, E., Belfer, I., Chabot-Dore, A.-J., Gris, P., Khoury, S. Tansley, S., Torosyan, Y., Zaykin, D.V., Bernhardt, O., de Oliveira Serrano, P., Gracely, R.H., Jain, D., Jarvelin, M.-R., Kaste, L.M., Kerr, K.F., Kocher, T., Lahdesmaki, R., Laniado, N., Laurie, C.C., Laurie, C.A., Mannikko, M., Meloto, C.B., Nackley, A.G., Nelson, S.C., Pesonen, P., Ribeiro-Dasilva, M.C., Rizzatti-Barbosa, C.M., Sanders, A.E., Schwahn, C., Sipila, K., Sofer, T., Teumer, A., Mogil, J.S., Fillingim, R.B., Greenspan, J.D., Ohrbach, R., Slade, G.D., Maixner, W., and Diatchenko, L. Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males. Pain, 160:579-591, 2019. (DOI: 10.1097/j.pain.0000000000001438)
  • ⊕⊕⊕⊕Martin, L.J., Acland, E.L., Cho, C., Gandhi, W., Chen, D., Corley, E., Kadoura, B., Levy, T., Mirali, S., Tohyama, S., Khan, S., MacIntyre, L.C., Carlson, E.N., Schweinhardt, P., and Mogil, J.S. Male-specific conditioned pain hypersensitivity in mice and humans.  Current Biology, 29:192-201.e4, 2019. (DOI: 10.1016/j.cub.2018.11.030)
  • Rosen, S., Ham, B., Haichin, M., Walters, I., Tohyama, S., Sotocinal, S.G., and Mogil, J.S. Increased pain sensitivity and decreased opioid analgesia in T cell-deficient mice and implications for sex differences. Pain, 160:358-366, 2019. (DOI: 10.1097/j.pain.0000000000001420) 
  • Baskozos, G., Dawes, J.M., Austin, J.S., Antunes-Martins, A., McDermott, L., Clark, A.J., McMahon, S.B., Mogil, J.S., Orengo, C., and Bennett, D.L. Comprehensive analysis of long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury. Pain, 160:463-485, 2019. (DOI: 10.1097/j.pain.0000000000001416)
  • Tansley, S.N., Tuttle, A.H., Wu, N., Tohyama, S., Dossett, K., Gerstein, L., Ham, B., Austin, J.-S., Sotocinal, S.G., and Mogil, J.S. Modulation of social behavior and dominance status by chronic pain in mice.  Genes Brain and Behavior, 18:e12514, 2019. (DOI: 10.1111/gbb.12514)
  • Mapplebeck, J.C.S., Dalgarno, R., Tu, Y.S., Moriarty, O., Beggs, S., Kwok, C.H.T., Halievski, K., Assi, S., Mogil, J.S., Trang, T., and Salter, M.W. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Pain, 159:1752-1763, 2018. (DOI: 10.1097/j.pain.0000000000001265) 
  • Uttam, S., Wong, C., Amorim, I.S., Jafarnejad, S.M., Tansley, S.N., Yang, J., Prager-Khoutorsky, M., Mogil, J.S., Gkogkas, C.G., and Khoutorsky, A. Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain. Neurobiology of Pain, 4:35-44, 2018. (DOI: 10.1016/j.ynpai.2018.04.001) 
  • Tuttle, A.H., Molinaro, M.J., Jethwa, J.F., Sotocinal, S.G., Prieto, J.C., Styner, M.A., Mogil, J.S., and Zylka, M.J. A deep neural network to assess spontaneous pain from mouse facial expressions. Molecular Pain, 14:1-29, 2018. (DOI: 10.1177/1744806918763658)
  • Rosen, S.F., Ham, B., Drouin, S., Boachie, N., Chabot-Dore, A.-J., Austin, J.-S., Diatchenko, L., and Mogil, J.S. T cell mediation of pregnancy analgesia affecting chronic pain in mice. Journal of Neuroscience, 37:9819-9827, 2017. (DOI: 10.1523/JNEUROSCI.2053-17.2017)
  • Martin, L.J., Smith, S.B., Khoutorsky, A., Magnussen, C.A., Samoshkin, A., Sorge, R.E., Cho, C., Yosefpour, N., Sivaselvachandran, S., Tohyama, S., Cole, T., Khong, T.M., Mir, E., Gibson, D.G., Wieskopf, J.S., Sotocinal, S.G., Austin, J.-S., Meloto, C.B., Gitt, J.H., Gkogkas, C., Sonenberg, N., Greenspan, J., Fillingim, R.B., Ohrbach, R., Slade, G.D., Knott, C., Dubner, R., Nackley, A.G., Ribeiro-da-Silva, A., Neely, G.G., Maixner, W., Zaykin, D.V., Mogil, J.S.*, and Diatchenko, L.*  Epiregulin and EGFR interactions are involved in pain processing.  Journal of Clinical Investigation, 127:3353-3363, 2017.   (*co-corresponding authors) (DOI: 10.1172/JCI87406)
  • ♦♦Moy, J.K., Khoutorsky, A., Asiedu, M.N., Black, B.J., Kuh, J.L., Barragan-Iglesias, P., Megat, S., Burton, M.D., Burgos-Vega, C.C., Melemedjian, O.K., Boitano, S., Vagner, J., Gkogkas, C.G., Pancrazio, J.J., Mogil, J.S., Dussor, G., Sonenberg, N., and Price, T.J. The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. Journal of Neuroscience, 37:7481-7499, 2017. (DOI: 10.1523/JNEUROSCI.0220-17.2017) 
  • Parisien, M., Khoury, S., Chabot-Dore, A.-J., Sotocinal, S.G., Slade, G.D., Smith, S.B., Fillingim, R.B., Ohrbach, R., Greenspan, J.D., Maixner, W., Mogil, J.S., Belfer, I., and Diatchenko, L. Effect of human genetic variability on gene transcription in dorsal root ganglia and association with pain phenotypes. Cell Reports, 19:1940-1952, 2017. (DOI: 10.1016/j.celrep.2017.05.018)
  • Tuttle, A.H., Tansley, S., Dossett, K., Tohyama, S., Khoutorsky, A., Maldonado-Bouchard, S., Stein, L., Gerstein, L., Crawhall-Duk, H., Pearl, R., Sukosd, M., Leger, P., Hardt, O., Yachnin, D., Austin, J.-S., Chan, C.M., Groves, I., Pooters, T., Martin, L.J., Sonenberg, N., Gkogkas, C.G., and Mogil, J.S. Social propinquity in rodents as measured by tube co-occupancy differs between inbred and outbred genotypes.  Proceedings of the National Academy of Sciences, USA, 114:5515-5520, 2017. (DOI: 10.1073/pnas.1703477114)
  • Khoutorsky, A., Sorge, R.E., Prager-Khoutorsky, M., Pawlowski, S.A., Longo, G., Jafarnejad, S.M., Tahmasebi, S., Martin, L.J., Pitcher, M.H., Gkogkas, C.G., Sharif-Naeini, R., Ribeiro-da-Silva, A., Bourque, C.W., Cervero, F., Mogil, J.S.*, and Sonenberg, N.* eIF2a phosphorylation controls thermal nociception. Proceedings of the National Academy of Sciences, USA, 113:11949-11954, 2016.  (*co-corresponding authors) (DOI: 10.1073/pnas1614047113)
  • Ultsch, A., Kringel, D., Kalso, E., Mogil, J.S., and Lotsch, J. A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity. Pain, 157:2747-2757, 2016. (DOI: 10.1097/j.pain.0000000000000694)
  • Kikusui, T., Ishio, Y., Nagasawa, M., Mogil, J.S., and Mogi, K. Early weaning impairs a social contagion of pain-related stretching behavior in mice. Developmental Psychobiology, 58:1101-1107, 2016. (DOI: 10.1002/dev.21443)
  • Young, E., Bryant, C., Lee, S., Nair, H., Dreher, K., Zhang, X., Palmer, A., Chung, J.M., Mogil, J.S., Chesler, E., and Lariviere, W. Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes Brain and Behavior, 15:604-615, 2016. (DOI: 10.1111/gbb.12302)
  • Kahle, K.T., Schmouth, J.F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganiere, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J.C., Sotocinal, S.G., Duan, J., Ward, C., Khanna, A.R., Mogil, J.S., Dion, P.A., Woolf, C.J., Inquimbert, P., and Rouleau, G.A. Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.  Science Signaling. 9:ra32, 2016. (DOI: 10.1126/scisignal.aad0163)
  • Daou, I., Beaudry, H., Ase, A.R., Wieskopf, J.S., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P. Optogenetic silencing of Nav1.8-positive afferents alleviates inflammatory and neuropathic pain. eNeuro, 3: e0140-15.2016, 2016. (DOI: 10.1523/ENEURO.0140-15.2016) 
  • Samoshkin, A., Convertino, M., Viet, C.T., Wieskopf, J.S., Marcovitz, J., Patel, P., Stone, L., Maixner, W., Mogil, J.S., Schmidt, B.L., Dokholyan, N.V., and Diatchenko, L.  Structural and functional interaction between six transmembrane μ-opioid receptor isoform and β2-adrenoceptors.  Science Reports, 5:18198, 2015. (DOI: 10.1038/srep18198)
  • Khoutorsky, A., Bonin, R.P., Sorge, R.E., Gkogkas, C., Pawlowski, S.A., Jafarnejad, S.M., Pitcher, M.H., Alain, T., Perez-Sanchez, J. Salter, E.W., Martin, L.J., Ribeiro-da-Silva, A., De Koninck, Y., Cervero, F., Mogil, J.S.* and Sonenberg, N.* Translational control of nociception via 4E-binding protein 1. eLife, 4:e12002, 2015.   (*co-corresponding authors) (DOI: 10.7554/eLife.12002)      
  • Martin, L.J., Piltonen, M.H., Gauthier, J., Convertino, M., Acland, E.L., Dokholyan, N.V., Mogil, J.S., Diatchenko, L., and Maixner, W.  Differences in the antinociceptive effects and binding properties of propranolol and bupranolol enantiomers. Journal of Pain, 16:1321-1333, 2015. (DOI: 10.1016/j.jpain.2015.09.004)
  • Sorge, R.E., Mapplebeck, J.C.S., Rosen, S., Beggs, S., Taves, S., Alexander, J.K., Martin, L.J., Austin, J.-S., Sotocinal, S.G., Chen, D., Yang, M., Shi, X.Q., Huang, H., Pillon, N.J., Bilan, P.J., Tu, Y., Klip, A., Ji, R.-R., Zhang, J., Salter, M.W. and Mogil, J.S. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nature Neuroscience, 18:1081-1083, 2015. (DOI: 10.1038/nn.4053) 
  • Segall, S.K., Shabalina, S.A., Meloto, C.B., Wen, X., Gauthier, J., Wiltshire, T., Cunningham, D., Tarantino, L., Tohyama, S., Martin, L.J., Mogil, J.S., and Diatchenko, L. Molecular genetic mechanisms of allelic specific regulation of murine Comt expression. Pain, 156:1965-1977, 2015. (DOI: 10.1097/j.pain.0000000000000258)
  • Wieskopf, J.S., Mathur, J. Limapichat, W., Post, M.R., Al-Qazzaz, M., Sorge, R.E., Martin, L.J., Zaykin, D.V., Smith, S.B., Freitas, K., Austin, J.-S., Dai, F., Zhang, J., Marcovitz, J., Tuttle, A.H., Slepian, P.M., Clarke, S., Drenan, R.M., Janes, J., Al Sharari, S., Segall, S.K., Aasvang, E.K., Lai, W., Bittner, R., Richards, C.I., Slade, G.D., Kehlet, H., Walker, J., Maskos, U., Changeux, J.-P., Devor, M., Maixner, W., Diatchenko, L., Belfer, I., Dougherty, D.A., Su, A.I., Lummis, S.C.R., Damaj, M.I., Lester, H.A., Patapoutian, A., and Mogil, J.S. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine, 7:287ra72, 2015. (DOI: 10.1126/scitranslmed.3009986)
  • Szabo, N.E., da Silva, R.V., Sotocinal, S.G., Zeilhofer, H.U., Mogil, J.S., and Kania, A. Hoxb8 intersection defines a role for Lmx1b in excitatory dorsal horn neuron development, spinofugal connectivity and nociception. Journal of Neuroscience, 35:5233-5246, 2015. (DOI: 10.1523/JNEUROSCI.4690-14.2015)
  • Martin, L.J., Hathaway, G., Isbester, K., Mirali, S., Acland, E.L., Niederstrasser, N., Slepian, P.M., Trost, Z., Bartz, J.A., Sapolsky, R.M., Sternberg, W.F., Levitin, D.J., and Mogil, J.S. Reducing social stress elicits emotional contagion of pain in mouse and human strangers. Current Biology, 25:326-332, 2015. (DOI: 10.1016/j.cub.2014.11.028)
  • Cahill, L.S., Laliberte, C.L., Liu, X.J., Bishop, J., Nieman, B.J., Mogil, J.S., Sorge, R.E., Jones, C.D., Salter, M.W., and Henkelman, R.M. Quantifying blood-spinal cord barrier permeability after peripheral nerve injury in the living mouse. Molecular Pain, 10:60, 2014. (DOI: 10.1186/1744-8069-10-60)
  • Wieskopf, J.S., Pan, Y.-X., Marcovitz, J., Tuttle, A.H., Majumdar, S., Pidakala, J., Pasternak, G.W., and Mogil, J.S. Broad spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene. Pain, 155:2063-2070, 2014. (DOI:10.1016/j.pain.2014.07.014)
  • Tang, S., Ding, Y., Sibille, E. Mogil, J.S., Lariviere, W.R., and Tseng, G.C. Imputation of truncated p-values for meta-analysis methods and its genomic application. Annals of Applied Statistics, 8:2150-2174, 2014. (DOI: 10.1214/14-AOAS747)
  • Sorge, R.E., Martin, L.J., Isbester, K.A., Sotocinal, S.G., Rosen, S., Tuttle, A.H., Wieskopf, J.S., Acland, E.L., Dokova, A., Kadoura, B., Leger, P., Mapplebeck, J.C.S., McPhail, M., Delaney, A., Wigerblad, G., Schumann, A.P., Quinn, T., Frasnelli, J., Svensson, C.I., Sternberg, W.F., and Mogil, J.S. Olfactory exposure to males, including human males, stresses rodents. Nature Methods, 11:629-632, 2014. (DOI:10.1038/nmeth.2935)
  • Farmer, M.A., Leja, A., Foxen-Craft, E., Chan, L., MacIntyre, L.C., Niaki, T., Chen, M., Mapplebeck, J.C.S., Tabry, V., Topham, L., Sukosd, M., Binik, Y.M., Pfaus, J.G., and Mogil, J.S. Pain reduces sexual motivation in female but not male mice. Journal of Neuroscience, 34:5747-5753, 2014. (DOI:10.1523/JNEUROSCI.5337-13.2014) 
  • Kristiansen, F.L., Olesen, A.E., Brock, C., Gazerani, P., Petrini, L., Mogil, J.S., and Drewes, A.M. The role of pain catastrophizing in experimental pain perception. Pain Practioner, 14:E136-E145, 2014. (DOI: 10.1111/papr.12150)  
  • Daou, I., Tuttle, A.H., Long, G., Wieskopf, J.S., Bonin, R., Ase, A., Wood, J.N., De Koninck, Y., Ribeiro-da-Silva, A., Mogil, J.S., and Seguela, P. Remote optogenetic activation and sensitization of pain pathways in freely moving mice. Journal of Neuroscience, 33:18631-18640, 2013. (DOI: 10.1523/JNEUROSCI.2424-13.2013)
  • Corder, G., Doolen, S., Donahue, R.R., Winter, M.K., Jutras, B.L., He, Y., Hu, X., Wieskopf, J.S., Mogil, J.S., Storm, D.R., Wang, Z.J., McCarson, K.E., and Taylor, B.K.  Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. Science, 341:1394-1399, 2013. (DOI: 10.1126/science.1239403)
  • Belfer, I., Segall, S.K., Lariviere, W.R., Smith, S.B., Dai, F., Slade, G.G., Rashid, N.U., Mogil, J.S., Campbell, C.M., Edwards, R.R., Liu, Q., Bair, E., Maixner, W., and Diatchenko, L.  Pain modality- and sex-specific effects of COMT functional variants. Pain, 154:1368-1376, 2013. (DOI: 10.1016/j.pain.2013.04.028) ††
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  • Kest, B., Hopkins, E., Palmese, C.A., Chen, Z.-P., Mogil, J.S., and Pintar, J.E. Morphine tolerance and dependence in nociceptin/orphanin FQ transgenic knock-out mice. Neuroscience, 104:217-222, 2001. (DOI: 10.1016/S0306-4522(01)00037-9)
  • Wan, Y., Wilson, S.G., Han, J.S., and Mogil, J.S. The effect of genotype on sensitivity to electroacupuncture analgesia. Pain, 91:5-13, 2001. (DOI: 10.1016/S0304-3959(00)00416-4)
  • Mogil, J.S., Grisel, J.E., Bales, J.R., Hayward, M.D., Rubinstein, M., Belknap, J.K.,and Low, M. Disparate spinal and supraspinal opioid antinociceptive responses in β-endorphin-deficient mutant mice.  Neuroscience, 101:709-717, 2000. (DOI: 10.1016/S0306-4522(00)00422-X)
  • Mogil, J.S., Chesler, E.J., Wilson, S.G., Juraska, J.M., and Sternberg, W.F.  Sex differences in thermal nociception and morphine antinociception in the rodent depend on genotype. Neuroscience and Biobehavioral Reviews, 24:375-389, 2000. (DOI: 10.1016/S0149-7634(00)00015-4)
  • Hain, H., Belknap, J.K., and Mogil, J.S. Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity. Journal of Pharmacology and Experimental Therapeutics, 291:444-449, 1999. (PMID: 10525057)
  • Flores, C.MWilson, S.G., and Mogil, J.S. Pharmacogenetic variability in neuronalnicotinic receptor-mediated antinociception. Pharmacogenetics, 9:619-625, 1999. (DOI: 10.1097/00008571-199910000-00008)
  • Grisel, J.E., Mogil, J.S., Grahame, N.J., Rubinstein, M., Belknap, J.K., Crabbe, J.C., and Low, M.  Ethanol oral self-administration is increased in mutant mice with decreased β-endorphin expression. Brain Research, 835:62-67, 1999. (DOI: 10.1016/S0006-8993(99)01384-0)
  • Kest, B., Wilson, S.G., and Mogil, J.S. Sex differences in supraspinal morphine analgesia are dependent on genotype.  Journal of Pharmacology and Experimental Therapeutics, 289:1370-1375, 1999. (PMID: 10336528)
  • Martìnez, V., Thakur, S., Mogil, J.S., Tachë, Y., and Mayer, E.A. Differential effects of chemical and mechanical colonic irritation on behavioral pain response to intraperitoneal acetic acid in mice. Pain, 81:179-186, 1999. (DOI: 10.1016/S0304-3959(99)00008-1)
  • Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M. Heritability of nociception. II. ‘Types’ of nociception revealed by genetic correlation analysis. Pain, 80:83-93, 1999. (DOI: 10.1016/S0304-3959(98)00196-1)
  • ♦♦Mogil, J.S., Wilson, S.G., Bon, K., Lee, S.E., Chung, K., Raber, P., Pieper, J.O., Hain, H.S., Belknap, J.K., Hubert, L., Elmer, G.I., Chung, J.M., and Devor, M. Heritability of nociception. I. Responses of eleven inbred mouse strains on twelve measures of nociception. Pain, 80:67-82, 1999. (DOI: 10.1016/S0304-3959(98)00197-3)
  • Mogil, J.S., Nessim, L.A., and Wilson, S.G. Strain-dependent effects of supraspinal orphanin FQ/nociceptin on thermal nociceptive sensitivity in mice. Neuroscience Letters, 261:147-150, 1999. (DOI: 10.1016/S0304-3940(99)00012-9)
  • Kest, B., Jenab, S., Brodsky, M., Sadowski, B., Belknap, J.K., Mogil, J.S., and Inturrisi, C.E. Mu and delta opioid receptor analgesia, binding density, and mRNA levels in mice selectively bred for high and low analgesia. Brain Research, 816:381-389, 1999. (DOI: 10.1016/S0006-8993(98)01141-X)
  • Kest, B., McLemore, G.L., Sadowski, B., Mogil, J.S., Belknap, J.K., and Inturrisi, C.E. Acute morphine dependence in mice selectively-bred for high and low analgesia. Neuroscience Letters, 256:120-122, 1998. (DOI: 10.1016/S0304-3940(98)00772-1)
  • Kest, B., Beckzowska, I., Franklin, S.O., Lee, C.E., Mogil, J.S., and Inturrisi, C.E. Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice. Brain Research, 805:131-137, 1998. (DOI: 10.1016/S0006-8993(98)00696-9)
  • Grisel, J.E., Farrier, D.E., Wilson, S.G., and Mogil, J.S. [Phe1Y(CH2-NH)Gly2] nociception-(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivo. European Journal of Pharmacology, 357:R1-R3, 1998. (DOI: 10.1016/S0014-2999(98)00567-6)
  • Mogil, J.S., Lichtensteiger, C.A., and Wilson, S.G. The effect of genotype on sensitivity to inflammatory nociception: characterization of resistant (A/J) and sensitive (C57BL/6J) inbred mouse strains. Pain, 76:115-125, 1998. (DOI: 10.1016/S0304-3959(98)00032-3)
  • Mogil, J.S., Shin, Y.-H., McCleskey, E.W., Kim, S.-C., and Nah, S.-Y. Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. Brain Research, 792:218-228, 1998. (DOI: 10.1016/S0006-8993(98)00133-4)
  • Sufka, K.J., Watson, G.S., Nothdurft, R.E., and Mogil, J.S. Scoring the mouse formalin test: validation study. European Journal of Pain, 2:351-358, 1998. (DOI: 10.1016/S1090-3801(98)90033-7)
  • Mogil, J.S. and Wilson, S.G. Nociceptive and morphine antinociceptive sensitivity of 129 and C57BL/6 inbred mouse strains: implications for transgenic knock-out studies. European Journal of Pain, 1:293-297, 1997. (DOI: 10.1016/S1090-3801(97)90038-0)
  • Mogil, J.S., Richards, S.P., O’Toole, L.A., Mitchell, S.R., Helms, M.L., Kest, B., and Belknap, J.K. Identification of sex-specific quantitative trait loci mediating non-opioid swim stress-induced analgesia in female mice.  Journal of Neuroscience, 17:7995-8002, 1997. (DOI: 10.1523/JNEUROSCI.17-20-07995.1997)
  • Mogil, J.S., Richards, S.P., O’Toole, L.A., Helms, M.L., Mitchell, S.R., and Belknap, J.K. Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by δ2-opioid receptors. Pain, 70:267-277, 1997. (DOI: 10.1016/S0304-3959(97)03333-2)
  • Tian, J.-H., Xu, W., Fang, Y., Mogil, J.S., Grisel, J.E., Grandy, D.K., and Han, J.-S. Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat. British Journal of Pharmacology, 120:676-680, 1997. (DOI: 10.1038/sj.bjp.0700942)
  • Kest, B., Lee, C.E., Mogil, J.S., and Inturrisi, C.E. Blockade of morphine supersensitivity by an antisense oligodeoxynucleotide targeting the delta opioid receptor (DOR-1). Life Sciences, 60:PL155-159, 1997. (DOI: 10.1016/S0024-3205(96)00704-7)
  • Tian, J.-H., Xu, W., Fang, Y., Grisel, J.E., Mogil, J.S., Grandy, D.K., and Han, J.-S. Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia. Neuroreport, 8:497-500, 1997. (DOI: 10.1097/00001756-199701200-00024)
  • Mogil, J.S. and Belknap, J.K. Sex and genotype determine the selective activation of neurochemically-distinct forms of swim stress-induced analgesia. Pharmacology, Biochemistry and Behavior, 56:61-66, 1997. (DOI: 10.1016/S0091-3057(96)00157-8)
  • Mogil, J.S., Grisel, J.E., Reinscheid, R.K., Civelli, O., Belknap, J.K., and Grandy, D.K.  Orphanin FQ is a functional anti-opioid peptide. Neuroscience, 75:333-337, 1996. (DOI: 10.1097/00001756-199609020-00012)
  • Grisel, J.E., Mogil, J.S., Belknap, J.K., and Grandy, D.K. Orphanin FQ acts as a supraspinal, but not a spinal, anti-opioid peptide.  Neuroreport, 7:2125-2129, 1996. (DOI: 10.1097/00001756-199609020-00012)
  • ♦♦Mogil, J.S., Grisel, J.E., Zhang, G., Belknap, J.K., and Grandy, D.K.  Functional antagonism of μ-, δ- and κ-opioid antinociception by orphanin FQ. Neuroscience Letters, 214:131-134, 1996. (DOI: 10.1016/0304-3940(96)12917-7)
  • Rubinstein, M.*, Mogil, J.S.*, Japón, M., Chan, E.C., Allen, R.G., and Low, M.J. Absence of opioid stress-induced analgesia in mice lacking β-endorphin by site-directed mutagenesis. Procedings of the National Academy of Sciences, USA, 93:3995-4000, 1996. (*co-first authors) (DOI: 10.1073/pnas.93.9.3995)
  • Mogil, J.S., Kest, B., Sadowski, B., and Belknap, J.K. Differential genetic mediation of sensitivity to morphine in genetic models of opiate sensitivity: influence of nociceptive assay. Journal of Pharmacology and Experimental Therapeutics, 276: 532-544, 1996. (PMID: 8632319)
  • Mogil, J.S., Sternberg, W.F., Balian, H., Liebeskind, J.C., and Sadowski, B. Opioid and non-opioid swim stress-induced analgesia: a parametric analysis in mice. Physiology and Behavior, 59: 123-132, 1996. (DOI: 10.1016/0031-9384(95)02073-X)
  • Kest, B., Brodsky, M., Sadowski, B., Mogil, J.S., and Inturrisi, C.E. Mu-opiate receptor (Mor-1) mRNA levels are altered in mice with differential analgesic sensitivity to the mu agonist, DAMGO. Analgesia, 1:498-501, 1995. (not MEDLINE indexed)
  • Sternberg, W.F., Mogil, J.S., Kest, B., Page, G.G., Leong, Y., Yam, V., and Liebeskind, J.C. Neonatal testosterone exposure influences neurochemistry of swim stress-induced analgesia in adult mice. Pain, 63:321-326, 1995. (DOI: 10.1016/0304-3959(95)00059-3)
  • Mogil, J.S., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines. Behavior Genetics, 25:397-406, 1995. (DOI: 10.1007/BF02197290)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C. 1,3-Di-o-tolylguanidine (DTG) differentially affects acute and tonic formalin pain: antagonism by rimcazole. Pharmacology, Biochemistry and Behavior, 52:175-178, 1995. (DOI: 10.1016/0091-3057(95)00085-B)
  • Vaccarino, F.J., Mogil, J.S., and Stinus, L. Chronic dopamine antagonism facilitates opiate-induced feeding. Journal of Psychiatric Neuroscience, 20:210-214, 1995. (PMID: 7786882) 
  • Belknap, J.K., Mogil, J.S., Helms, M.L., O’Toole, L.A., Richards, S.P., and Bergeson, S.E. Localization to chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 mouse strains.  Life Sciences, 57:PL117-124, 1995. (DOI: 10.1016/0024-3205(95)02040-P)
  • Kest, B., Mogil, J.S., Sternberg, W.F., Pechnick, R.N., and Liebeskind, J.C. Antinociception following 1,3-di-o-tolylguanidine (DTG), a selective sigma receptor ligand. Pharmacology, Biochemistry and Behavior, 50:587-592, 1995. (DOI: 10.1016/0091-3057(94)00346-7)
  • Mogil, J.S., Marek, P., Flodman, P., Spence, M.A., Sternberg, W.F., Kest, B., Sadowski, B., and Liebeskind, J.C. One or two genetic loci mediate high opiate analgesia in selectively bred mice. Pain, 60:125-135, 1995. (DOI: 10.1016/0304-3959(94)00098-Y)
  • Mogil, J.S., Marek, P., O’Toole, L.A., Helms, M.L., Sadowski, B., Liebeskind, J.C., and Belknap, J.K.  Mu-opiate receptor binding is up-regulated in mice selectively bred for high stress-induced analgesia.  Brain Research, 653:16-22, 1994. (DOI: 10.1016/0006-8993(94)90366-2)
  • Mogil, J.S., Sternberg, W.F., Kest, B., Marek, P., and Liebeskind, J.C. Sex differences in the antagonism of swim stress-induced analgesia: effects of gonadectomy and estrogen replacement. Pain, 253:17-25, 1993. (DOI: 10.1016/0304-3959(93)90050-Y)
  • Marek, P., Mogil, J.S., Belknap, J.K., Sadowski, B., and Liebeskind, J.C.  Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalties. Brain Research, 608:353-357, 1993. (DOI: 10.1016/0006-8993(93)91479-C)
  • Mogil, J.S., Marek, P., Yirmiya, R., Balian, H., Sadowski, B., Taylor, A.N., and Liebeskind, J.C. Antagonism of the non-opioid component of ethanol-induced analgesia by the NMDA receptor antagonist MK-801. Brain Research, 602:126-130, 1993. (DOI: 10.1016/0006-8993(93)90251-H)
  • Marek, P., Mogil, J.S., Sternberg, W.F., Panocka, I., and Liebeskind, J.C. N-Methyl-D-aspartic acid (NMDA) receptor antagonist MK-801 blocks non-opioid stress-induced analgesia. II. Studies using three different water temperature paradigms and selectively bred mice. Brain Research, 578:197-203, 1992. (DOI: 10.1016/0006-8993(92)90248-8)
  • Ben-Eliyahu, S., Marek, P., Vaccarino, A.L., Mogil, J.S., Sternberg, W.F., and Liebeskind, J.C. The NMDA receptor antagonist MK-801 prevents long-lasting non-associative morphine tolerance in the rat. Brain Research, 575:304-308, 1992. (DOI: 10.1016/0006-8993(92)90094-P)